Electroconvulsive therapy: a novel hypothesis for the involvement of purinergic signalling
نویسندگان
چکیده
منابع مشابه
Acupuncture: a novel hypothesis for the involvement of purinergic signalling.
The hypothesis is summarised schematically in Fig. 1. It is proposed that mechanical deformation of the skin by needles and application of heat or electrical current leads to release of large amounts of ATP from keratinocytes, fibroblasts and other cells in skin; the ATP then occupies specific receptor subtypes expressed on sensory nerve endings in the skin and tongue; the sensory nerves send i...
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15 صفحه اولPurinergic signalling.
While there were early papers about the extracellular actions of purines, the role of ATP as a purinergic neurotransmitter in nonadrenergic, noncholinergic nerves in the gut and bladder in 1972 was a landmark discovery, although it met considerable resistance for the next 20 years. In the early 1990s, receptors for purines were cloned: four P1 receptor subtypes and seven P2X ionotropic and eigh...
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The ventrolateral medulla has a critical role in the generation and patterning of respiration via an extensive network of respiratory neurones. We have investigated the effects of activating purinergic P2 receptors within the ventrolateral medulla of the anaesthetised rat on the overall pattern of respiratory activity. In addition, using immunohistochemical techniques, we have identified the su...
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ژورنال
عنوان ژورنال: Purinergic Signalling
سال: 2011
ISSN: 1573-9538,1573-9546
DOI: 10.1007/s11302-011-9242-y